Gastrointestinal Hepatobiliary Viewed in its simplest form, the gastrointestinal tract is a hollow digestive tube that extends through the center of the body from the mouth to the anus. The walls of the tube are lined with a diverse number of epithelial cells that function well at transmembrane secretion and absorption and maintain the barrier that protects the host from microbial pathogens. The barrier consists of the intact mucosal surface and a population of resident immune cells. The primary function of the gastrointestinal system is digestion and nutrient uptake. The epithelial cells have a relatively short life, with most cells living between 48 and 72 hours. Because of the constant turnover of cells, it is difficult for pathogens to colonize the gastrointestinal tract. However, the disadvantage of the high rate of cell turnover is that the epithelial cells are more susceptible to mutagenic compounds and tumor formation.
All of the liquid and solid material ingested, along with bacteria, is carried through the tube. Bacteria colonize the areas of the tube that offer a suitable environment for growth. Soon after birth, a microbiota is established in each part of the tube. The oral cavity and the colon are at opposite ends of the tube and are heavily colonized with bacteria. The central part of the tube, the stomach, duodenum, jejunum, and the proximal half of the ileum, are lightly colonized. Each portion of the gastrointestinal tract has special defense mechanisms that protect it from pathogenic microorganisms. When pathogenic microorganisms or their toxins breach these defense mechanisms, disease can occur.
MBBS – PGIMS Rohtak
MD Radio-diagnosis (2013-2016), SGPGIMS Lucknow
Consultant radiologist Jindal hospital, Hisar, Haryana
Ex senior resident AIIMS, New Delhi
PDCC (Neuro-radiology) SGPGIMS Lucknow
DNB Radio-diagnosis (2018-2019)
PDCC (Gastro-radiology) 2019-2020, SGPGIMS Lucknow
Dr Rohit Agarwal is an interventional radiologist with an experience of 8 years in the field of diagnostic and interventional radiology. He received his training in the field of interventional radiology and endovascular sciences from Sir Gangaram Hospital, New Delhi, SGPGI, lucknow and Bach Mai Hospital, Hanoi. Dr. Rohit Agarwal is consultant in the department of interventional Radiology in Medanta hospital Lucknow with over 8 years of experience in Radiology and Interventional Radiology. He did his MBBS from KGMC, Lucknow followed by post graduation in Radiology from prestigious Dr RML Hospital and PGIMER New Delhi. After completing his training in Radiology he went for superspeciality training in the field of Interventional and vascular Radiology from prestigious Sir Gangaram Hospital, New Delhi and SGPGI, Lucknow.
